Identification of an acetonitrile addition impurity formed during peptide disulfide bond reduction using dithiothreitol and Tris(2-carboxyethyl)phosphine

Author:

Zhao Eileen,St-Jean Frédéric,Robinson Sarah J.,Sirois Lauren E.,Pellett Jackson,Al-Sayah Mohammad A.

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference30 articles.

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2. Synthetic therapeutic peptides: science and market;Vlieghe;Drug Discov. Today,2010

3. Peptide therapeutics market: forecast and analysis 2015–2025;Ghosh;Chim. Oggi,2016

4. Peptide based therapeutics and their use for the treatment of neurodegenerative and other diseases;Baig;Biomed. Pharmacother.,2018

5. Stabilization of functional proteins by introduction of multiple disulfide bonds;Matsumura;Methods Enzymol.,1991

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