A direct RT qPCR method for quantification of retrovirus-like particles in biopharmaceutical production with CHO cells

Author:

Hussain MusaddeqORCID,Rayfield William J.ORCID,Roush David J.

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference17 articles.

1. Endogenous origin of defective retrovirus like particles from a recombinant Chinese hamster ovary cell line;Anderson;Virology,1991

2. Mammalian cells in culture frequently release type C viruses;Lieber;Science,1973

3. Recent studies on retrovirus-like particles in Chinese hamster ovary cells;Dinowitz;Dev. Biol. Stand.,1992

4. Biological and molecular characterization of an endogenous retrovirus present in CHO/HBs-A Chinese hamster cell line;Hojman;Dev. Biol. Stand.,1989

5. Characterisation of endogenous retrovirus in rodent cell lines used for production of biologicals;Shepherd;Biologicals,2003

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