Distinct chemical degradation pathways of AAV1 and AAV8 under thermal stress conditions revealed by analytical anion exchange chromatography and LC-MS-based peptide mapping-Reference-Cited by-同舟云学术

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Distinct chemical degradation pathways of AAV1 and AAV8 under thermal stress conditions revealed by analytical anion exchange chromatography and LC-MS-based peptide mapping

Published:2024-12 Issue: Volume:251 Page:116452
ISSN:0731-7085
Container-title:Journal of Pharmaceutical and Biomedical Analysis
language:en
Short-container-title:Journal of Pharmaceutical and Biomedical Analysis

Author:

Xing Tao,Li Shuai,Tang Shuli,Huang Yu,Liu Gaoyuan,Yan Yuetian,Liu Dingjiang,Wang Shunhai,Zhi Li,Shameem Mohammed,Li Ning

Funder

Regeneron Pharmaceuticals

Publisher

Elsevier BV

Reference35 articles.

1. Basic biology of adeno-associated virus (AAV) vectors used in gene therapy;Balakrishnan;Curr. gene Ther.,2014

2. Adeno-associated virus vector as a platform for gene therapy delivery;Wang;Nat. Rev. Drug Discov.,2019

3. From virus evolution to vector revolution: use of naturally occurring serotypes of adeno-associated virus (AAV) as novel vectors for human gene therapy;Grimm;Curr. gene Ther.,2003

4. Engineering adeno-associated virus vectors for gene therapy;Li;Nat. Rev. Genet.,2020

5. Adeno-associated virus: fit to serve;Zinn;Curr. Opin. Virol.,2014

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