Rapid and sensitive UHPLC-DAD method for simultaneous determination of sofosbuvir and ledipasvir in human serum

Author:

Majnooni Mohammad Bagher,Miraghaee Seid-Shahram,Keshavarzi Samira,Mohammadi Bahareh,Sajadimajd Soraya,Hatami Razieh,Bahrami GholamrezaORCID

Funder

Bakhtarbioshimi pharmaceutical company

Kermanshah University of Medical Sciences

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference16 articles.

1. Efficacy of ledipasvir plus sofosbuvir for 8 or 12 weeks in patients with hepatitis C virus genotype 2 infection;Gane;Gastroenterology,2017

2. The epidemiology of hepatitis C virus in Iran: systematic review and meta-analyses;Mahmud;Sci. Rep.,2018

3. New direct-acting antivirals in hepatitis C therapy: a review of sofosbuvir, ledipasvir, daclatasvir, simeprevir, paritaprevir, ombitasvir and dasabuvir;McConachie;Expert Rev. Clin. Pharmacol.,2016

4. Application of TLC densitometric method for simultaneous estimation of the newly co-formulated antiviral agents ledipasvir and sofosbuvir in their tablet dosage form;Salama;Anal. Chem. Lett.,2017

5. Assay and dissolution methods development and validation for simultaneous determination of sofosbuvir and ledipasvir by RP-HPLC method in tablet dosage forms;Hassouna;J. Forensic Sci. Criminal Inv.,2017

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