Bioanalytical method development and validation for a large peptide HIV fusion inhibitor (Enfuvirtide, T-20) and its metabolite in human plasma using LC

Bioanalytical method development and validation for a large peptide HIV fusion inhibitor (Enfuvirtide, T-20) and its metabolite in human plasma using LC–MS/MS

Published:2005-07 Issue:3 Volume:38 Page:487-496
ISSN:0731-7085
Container-title:Journal of Pharmaceutical and Biomedical Analysis
language:en
Short-container-title:Journal of Pharmaceutical and Biomedical Analysis

Author:

Chang D.,Kolis S.J.,Linderholm K.H.,Julian T.F.,Nachi R.,Dzerk A.M.,Lin P.P.,Lee J.W.,Bansal S.K.

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference11 articles.

1. A Synthetic Peptide from HIV-1 gp41 Is a Potent Inhibitor of Virus-Mediated Cell—Cell Fusion

2. Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry

3. High-speed liquid chromatography/tandem mass spectrometry for the determination of drugs in biological samples

4. A Mass Spectrometric Method for Quantitation of Intact Insulin in Blood Samples

5. Immunoprecipitation and liquid chromatographic–mass spectrometric determination of the peptide glucose-dependent insulinotropic polypeptides GIP1-42 and GIP3-42 from human plasma samples

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