Simultaneous determination of curcumin, tetrahydrocurcumin, quercetin, and paeoniflorin by UHPLC-MS/MS in rat plasma and its application to a pharmacokinetic study

Author:

Yu Weilan,Wen Dingsheng,Cai Dake,Zheng Juntao,Gan Haining,Jiang Fulin,Liu Xiaolin,Lao Biaochang,Yu Weibang,Guan Yanping,Zhong Guoping

Funder

National Key Research and Development Program of China during the 13th five year plan

Guangdong Provincial Science and Technology Project

National Key Research and Development Program

Guangdong Science and Technology Planning Project

Guangdong Natural Science Foundation

Guangdong Provincial Key Laboratory of Construction Foundation

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference30 articles.

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2. Curcumin: from ancient medicine to current clinical trials;Hatcher;Cell. Mol. Life Sci.,2008

3. Anticancer potential of curcumin: preclinical and clinical studies;Aggarwal;Anticancer Res.,2003

4. The metabolism and excretion of curcumin (1,7-bis-(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) in the rat;Holder;Xenobiotica,1978

5. Bringing curcumin to the clinic in Cancer prevention: a review of strategies to enhance bioavailability and efficacy;Mahran;AAPS J.,2017

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