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Heparin and homogeneous model heparin oligosaccharides form distinct complexes with protamine: Light scattering and zeta potential analysis

  • Published:2017-06 Issue: Volume:140 Page:113-121
  • ISSN:0731-7085
  • Container-title:Journal of Pharmaceutical and Biomedical Analysis
  • language:en
  • Short-container-title:Journal of Pharmaceutical and Biomedical Analysis

Author:

Sommers Cynthia D.,Ye Hongping,Liu Jian,Linhardt Robert J.,Keire David A.

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference29 articles.

1. Heparin-induced thrombocytopenia and cardiac surgery;Warkentin;Ann. Thorac. Surg.,2003

2. Anti-protamine-heparin antibodies: incidence, clinical relevance, and pathogenesis;Bakchoul;Blood,2013

3. The immunogenicity of therapeutic proteins;Schellekens;Discov. Med.,2010

4. Clinical practice. Heparin-induced thrombocytopenia;Arepally;N. Engl. J. Med.,2006

5. Characterization of unfractionated heparin: comparison of materials from the last 50 years;Mulloy;Thromb. Haemost.,2000

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