LC–MS/MS assay for the quantitation of the HDAC inhibitor belinostat and five major metabolites in human plasma-Reference-Cited by-同舟云学术

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LC–MS/MS assay for the quantitation of the HDAC inhibitor belinostat and five major metabolites in human plasma

Published:2013-07 Issue: Volume:81-82 Page:89-98
ISSN:0731-7085
Container-title:Journal of Pharmaceutical and Biomedical Analysis
language:en
Short-container-title:Journal of Pharmaceutical and Biomedical Analysis

Author:

Kiesel Brian F.,Parise Robert A.,Tjørnelund Jette,Christensen Mette K.,Loza Einars,Tawbi Hussein,Chu Edward,Kummar Shivaani,Beumer Jan H.

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference8 articles.

1. Role of histone deacetylases and their inhibitors in cancer biology and treatment;Beumer;Curr. Clin. Pharmacol.,2010

2. Novel sulphonamide derivatives as inhibitors of histone deacetylase;Finn;Helvet. Chim. Acta,2005

3. Belinostat: a new broad acting antineoplastic histone deacetylase inhibitor;Gimsing;Expert Opin. Investig. Drugs,2009

4. Belinostat in combination with carboplatin and paclitaxel (BelCaP) for treatment of bladder cancer – a pharmacokinetic study of exposure to belinostat and its metabolites;Jones;Eur. J. Cancer,2011

5. Phase I pharmacokinetics and metabolic pathway of belinostat in patients with hepatocellular carcinoma;Wang;J. Clin. Oncol.,2010

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1. Liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) methods for the therapeutic drug monitoring of cytotoxic anticancer drugs: An update;Journal of Chromatography B;2024-04

2. The effect of liver dysfunction on the pharmacokinetic disposition of belinostat and its five metabolites in patients with advanced cancers;Cancer Chemotherapy and Pharmacology;2024-03-14

3. Phase 1 study of belinostat and adavosertib in patients with relapsed or refractory myeloid malignancies;Cancer Chemotherapy and Pharmacology;2023-03

4. Identification and Characterization of in vitro Metabolites of Belinostat by Rat Liver Microsomes using Ultra Performance Liquid Chromatography Coupled with Tandem Mass Spectrometry;Indian Journal of Pharmaceutical Education and Research;2022-01-27

5. Development and validation of an LC–MS/MS generic assay platform for small molecule drug bioanalysis;Journal of Pharmaceutical and Biomedical Analysis;2021-09

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