An LC-MS/MS method for determination of tenofovir (TFV) in human plasma following tenofovir alafenamide (TAF) administration: Development, validation, cross-validation, and use of formic acid as plasma TFV stabilizer

Author:

Xiao Deqing,Ling Kah Hiing John,Tarnowski Thomas,Majeed Sophia R.,German Polina,Kearney Brian P.,Zhao Yuwen,Chen Yuan-Shek,Ma Lili,zhang Tianyi

Funder

Gilead Sciences

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference54 articles.

1. Tenofovir alafenamide (TAF) as the successor of tenofovir disoproxil fumarate (TDF);De Clercq;Biochem. Pharmacol.,2016

2. Intracellular activation of tenofovir alafenamide and the effect of viral and host protease inhibitors;Birkus;Antimicrob. Agents Chemother.,2016

3. Intestinal behavior of the ester prodrug tenofovir DF in humans;Geboers;Int. J. Pharm.,2015

4. Selective intracellular activation of a novel prodrug of the human immunodeficiency virus reverse transcriptase inhibitor tenofovir leads to preferential distribution and accumulation in lymphatic tissue;Lee;Antimicrob. Agents Chemother.,2005

5. Advances in nucleotide antiviral development from scientific discovery to clinical applications: tenofovir disoproxil fumarate for hepatitis B;Lou;J Clin Transl Hepatol,2013

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