Cutting-edge mass spectrometry strategy based on imaged capillary isoelectric focusing (icIEF) technology for characterizing charge heterogeneity of monoclonal antibody-Reference-Cited by-同舟云学术

Cutting-edge mass spectrometry strategy based on imaged capillary isoelectric focusing (icIEF) technology for characterizing charge heterogeneity of monoclonal antibody

Published:2023-01 Issue: Volume:660 Page:114961
ISSN:0003-2697
Container-title:Analytical Biochemistry
language:en
Short-container-title:Analytical Biochemistry

Author:

Zhang Xiaoxi,Chen Tong^ORCID,Li Victor,Bo Tao,Du Min,Huang Tiemin

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference24 articles.

1. Comprehensive characterization of monoclonal antibody by Fourier transform ion cyclotron resonance mass spectrometry;Jin;mAbs,2019

2. N-glycosylation heterogeneity and the influence on structure, function and pharmacokinetics of monoclonal antibodies and Fc fusion proteins;Higel;Eur. J. Pharm. Biopharm.,2016

3. Antibody structure, instability, and formulation;Wang;Pharm. Sci.,2007

4. Development issues: antibody stability, developability, immunogenicity, and comparability,2012

5. Heterogeneity of monoclonal antibodies revealed by charge-sensitive methods;Vlasak;Curr. Pharmaceut. Biotechnol.,2008

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