Unlike other chemicals, etoposide (a topoisomerase-II inhibitor) produces peak mutagenicity in primary spermatocytes of the mouse
Author:
Publisher
Elsevier BV
Subject
Health, Toxicology and Mutagenesis,Genetics,Molecular Biology
Reference22 articles.
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2. Mutagenicity and carcinogenicity of topoisomerase-interactive agents;Anderson;Mutation Res.,1994
3. Etoposide and teniposide: in vivo and in vitro genotoxic studies;Larripa;Drug Invest.,1992
4. Potent clastogenicity of the human carcinogen etoposide to the mouse bone marrow and mouse lymphoma L5178Y cells: comparison to Salmonella responses;Ashby;Environ. Mol. Mutagen.,1994
5. Chromosome band 11q23 translocation breakpoints are DNA topoisomerase II cleavage sites;Felix;Cancer Res.,1995
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