Genotoxicity of 3′-azido-3′-deoxythymidine in the human lymphoblastoid cell line, TK6: relationships between DNA incorporation, mutant frequency, and spectrum of deletion mutations in HPRT

Author:

Sussman Hillary E,Olivero Ofelia A,Meng Quanxin,Pietras Sara M,Poirier Miriam C,O'Neill J.Patrick,Finette Barry A,Bauer Michael J,Walker Vernon E

Publisher

Elsevier BV

Subject

Health, Toxicology and Mutagenesis,Genetics,Molecular Biology

Reference24 articles.

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2. U.S. Public Health Service recommendations for human immunodeficiency virus counselling and voluntary testing for pregnant women, MMWR, 44, 1995, 1–15.

3. Maternal viral load, zidovudine treatment, and the risk of transmission of human immunodeficiency virus type 1 from mother to infant;Sperling;N. Engl. J. Med.,1996

4. Nonclinical toxicology studies with zidovudine: genetic toxicity tests and carcinogenicity bioassays in mice and rats;Ayers;Fundam. Appl. Toxicol.,1996

5. Protection against AZT-induced mutagenesis at the HGPRT locus in a human cell line by WR-151326;Grdina;Int. J. Radiat. Oncol., Biol., Phys.,1992

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