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Spontaneous mutagenesis in mammalian cells is caused mainly by oxidative events and can be blocked by antioxidants and metallothionein

  • Published:1998-06 Issue:1-2 Volume:402 Page:103-110
  • ISSN:0027-5107
  • Container-title:Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis
  • language:en
  • Short-container-title:Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Author:

Rossman Toby G.,Goncharova Ekaterina I.

Publisher

Elsevier BV

Subject

Health, Toxicology and Mutagenesis,Genetics,Molecular Biology

Reference58 articles.

1. Increased mutation rate at the hprt locus accompanies microsatellite instability in colon cancer;Eshleman;Oncogene,1995

2. DNA mismatch binding defects, DNA damage tolerance, and mutataor phenotypes in human colorectal carcinoma cell lines;Branch;Cancer Res.,1995

3. Mutator phenotype may be required for multi-stage carcinogenesis;Loeb;Cancer Res.,1991

4. Endogenous DNA damage as related to cancer and aging;Ames;Mutation Res.,1989

5. Endogenous DNA adducts: potential and paradox;Marnett;Chem. Res. Toxicol.,1993

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