Study of the long-term carcinogenicity potential of D-003, a mixture of high molecular weight sugarcane wax acids, in mice

Author:

Noa M.,Gámez R.,Más R.,Gutiérrez A.,Mendoza N.,Pardo B.,Marrero G.,Curveco D.,Goicochea E.,García H.,Pérez Y.,González R.M.

Publisher

Elsevier BV

Subject

Toxicology,General Medicine,Food Science

Reference48 articles.

1. Effects of D-003, a new compound purified from sugar cane wax, on platelet aggregation in healthy volunteers: a randomized, double-blind clinical study;Arruzazabala;Clin. Drug Invest.,2002

2. Assessment of the effects of D-003, a new anti-platelet and hypocholesterolemic compound on healthy volunteers: a Phase I clinical study;Castaño;Drugs R&D,2002

3. Effects of D-003 (5–40mg/day) on lipid profile of patients with type II hypercholesterolemia: a Phase II clinical study;Castaño;Clin. Drug Invest.,2003

4. Effects of D-003 on lipid profile and lipid peroxidation in healthy volunteers;Castaño;Clin. Drug Invest.,2003

5. CDER, 2001. US Department of Health and Human Services, Center for Drug Evaluation and Research, May 2001. Guidance for industry: statistical aspects of the design, analysis and interpretation of chronic rodent carcinogenicity studies of pharmaceuticals. Draft Guidance. Pharm/Tox.

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