DHA2, a synthesized derivative of bisbibenzyl, exerts antitumor activity against ovarian cancer through inhibition of XIAP and Akt/mTOR pathway

Author:

Pang Yingxin,Si Manfei,Sun Bin,Niu Leilei,Xu Xia,Lu Tao,Yuan HuiqingORCID,Lou Hongxiang

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Toxicology,General Medicine,Food Science

Reference58 articles.

1. Mechanism of taxol-induced apoptosis in human SKOV3 ovarian carcinoma cells;Ahn;J. Cell. Biochem.,2004

2. AKT and mTOR phosphorylation is frequently detected in ovarian cancer and can be targeted to disrupt ovarian tumor cell growth;Altomare;Oncogene,2004

3. AIF promotes chromatinolysis and caspase-independent programmed necrosis by interacting with histone H2AX;Artus;EMBO J.,2010

4. XIAP regulates Akt activity and caspase-3-dependent cleavage during cisplatin-induced apoptosis in human ovarian epithelial cancer cells;Asselin;Cancer Res.,2001

5. Regulation of cell death protease caspase-9 by phosphorylation;Cardone;Science,1998

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3