Cytochrome P450 4A11 inhibition assays based on characterization of lauric acid metabolites

Author:

Choi Yeon Jung,Zhou Yuanyuan,Lee Ji-Yoon,Ryu Chang Seon,Kim Young Ho,Lee Kiho,Kim Sang Kyum

Funder

Ministry of Education of the Republic of Korea

National Research Foundation (NRF) of Korea

Priority Research Centers Program

Korean Government (MEST)

Publisher

Elsevier BV

Subject

Toxicology,General Medicine,Food Science

Reference63 articles.

1. Involvement of cytochrome P450 2E1 in the (ω -1)-hydroxylation of oleic acid in human and rat liver microsomes;Adas;J. Lipid Res.,1998

2. Requirement for omega and (omega-1)-hydroxylations of fatty acids by human cytochromes P450 2E1 and 4A11;Adas;J. Lipid Res.,1999

3. The human FA2H gene encodes a fatty acid 2-hydroxylase;Alderson;J. Biol. Chem.,2004

4. The flavonoids diosmetin and luteolin exert synergistic cytostatic effects in human hepatoma HepG2 cells via CYP1A-catalyzed metabolism, activation of JNK and ERK and p53/p21 upregulation;Androutsopoulos;J. Nutr. Biochem.,2013

5. Dietary flavonoids in cancer therapy and prevention: substrates and inhibitors of cytochrome P450 CYP1 enzymes;Androutsopoulos;Pharmacol. Ther.,2010

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