Irinotecan decreases intestinal UDP-glucuronosyltransferase (UGT) 1A1 via TLR4/MyD88 pathway prior to the onset of diarrhea
Author:
Funder
National Institutes of Health
National Institute on Drug Abuse
National Cancer Institute
Publisher
Elsevier BV
Subject
Toxicology,General Medicine,Food Science
Reference36 articles.
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4. Effect of the acute phase response induced by endotoxin administration on the expression and activity of UGT isoforms in rats;Alkharfy;Drug Metabol. Lett.,2008
5. The reduction of oxidative stress by nanocomposite Fullerol decreases mucositis severity and reverts leukopenia induced by Irinotecan;Arifa;Pharmacol. Res.,2016
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