Development and application of a population physiologically based pharmacokinetic model for florfenicol and its metabolite florfenicol amine in cattle

Author:

Yang Fan,Lin ZhoumengORCID,Riviere Jim E.,Baynes Ronald E.

Funder

National Natural Science Foundation of China

China Scholarship Council

USDA/NIFA FARAD

Publisher

Elsevier BV

Subject

Toxicology,General Medicine,Food Science

Reference57 articles.

1. Tissue concentrations and pharmacokinetics of florfenicol in male veal calves given repeated doses;Adams;Am. J. Vet. Res.,1987

2. Effect of three anthelmentics on disposition kinetics of florfenicol in goats;Atef;Food Chem. Toxicol.,2010

3. Health concerns and management of select veterinary drug residues;Baynes;Food Chem. Toxicol.,2016

4. Florfenicol in non-lactating dairy cows: pharmacokinetics, binding to plasma proteins, and effects on phagocytosis by blood neutrophils;Bretzlaff;J Vet Pharmacol Ther,1987

5. Use of probabilistic modeling within a physiologically based pharmacokinetic model to predict sulfamethazine residue withdrawal times in edible tissues in swine;Buur;Antimicrob. Agents Chemother.,2006

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