α-Humulene inhibits hepatocellular carcinoma cell proliferation and induces apoptosis through the inhibition of Akt signaling

Author:

Chen Hao,Yuan Jingquan,Hao Ji,Wen Yanzhang,Lv Yibing,Chen Lu,Yang XinzhouORCID

Funder

National Natural Science Foundation of China

Wuhan Applied Basic Research Program of Science and Technology

Publisher

Elsevier BV

Subject

Toxicology,General Medicine,Food Science

Reference47 articles.

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2. Pharmacokinetics and tissue distribution of the sesquiterpene α-humulene in mice;Chaves;Planta Med.,2008

3. Essential oil derived from Eupatorium adenophorum Spreng. mediates anticancer effect by inhibiting STAT3 and AKT activation to induce apoptosis in hepatocellular carcinoma;Chen;Front. Pharmacol.,2018

4. Involvement of PI3K/PTEN/AKT/mTOR pathway in invasion and metastasis in hepatocellular carcinoma: association with MMP‐9;Chen;Hepatol. Res.,2009

5. Antitumor properties of the leaf essential oil of Zornia brasiliensis;Costa;Planta Med.,2015

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