A 35kD Phyllanthus niruri protein modulates iron mediated oxidative impairment to hepatocytes via the inhibition of ERKs, p38 MAPKs and activation of PI3k/Akt pathway

Author:

Bhattacharyya Sudip,Pal Pabitra Bikash,Sil Parames C.

Publisher

Elsevier BV

Subject

Toxicology,General Medicine,Food Science

Reference87 articles.

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2. Tumor necrosis factor-alpha-induced reactive oxygen species formation is mediated by JNK1-dependent ferritin degradation and elevation of labile iron pool;Antosiewicz;Free Radic. Biol. Med.,2007

3. The pathology of hepatic iron overload, a free radical mediated process?;Bacon;Hepatology,1990

4. Ferric reducing/antioxidant power assay: direct measure of total antioxidant activity of biological fluids and modified version for simultaneous measurement of total antioxidant power and ascorbic acid concentration;Benzie;Methods Enzymol.,1999

5. Protein isolate from the herb, Phyllanthus niruri, protects liver from acetaminophen induced toxicity;Bhattacharjee;Biomed. Res.,2006

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