Revisiting silibinin as a novobiocin-like Hsp90 C-terminal inhibitor: Computational modeling and experimental validation-Reference-Cited by-同舟云学术

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Revisiting silibinin as a novobiocin-like Hsp90 C-terminal inhibitor: Computational modeling and experimental validation

Published:2019-10 Issue: Volume:132 Page:110645
ISSN:0278-6915
Container-title:Food and Chemical Toxicology
language:en
Short-container-title:Food and Chemical Toxicology

Author:

Cuyàs Elisabet,Verdura Sara^ORCID,Micol Vicente^ORCID,Joven Jorge^ORCID,Bosch-Barrera Joaquim^ORCID,Encinar José Antonio,Menendez Javier A.^ORCID

Funder

Spanish Ministry of Science and Innovation

European Regional Development Fund, Spain

Fundació Oncolliga Girona

Vicente Micol laboratory

Spanish Ministry of Economy and Competitiveness (MINECO)

CIBER

Health Research and Innovation Strategic Plan

MINECO

Generalitat Valenciana

Publisher

Elsevier BV

Subject

Toxicology,General Medicine,Food Science

Reference90 articles.

1. Milk thistle (Silybum marianum): a concise overview on its chemistry, pharmacological, and nutraceutical uses in liver diseases;Abenavoli;Phytother Res.,2018

2. Silibinin inhibits constitutive activation of Stat3, and causes caspase activation and apoptotic death of human prostate carcinoma DU145 cells;Agarwal;Carcinogenesis,2007

3. Modulation of chaperone function and cochaperone interaction by novobiocin in the C-terminal domain of Hsp90: evidence that coumarin antibiotics disrupt Hsp90 dimerization;Allan;J. Biol. Chem.,2006

4. Hsp90, an unlikely ally in the war on cancer;Barrott;FEBS J.,2013

5. Discovery of nonnucleoside inhibitors of polymerase from infectious pancreatic necrosis virus(IPNV);Bello-Pérez;Drug Des. Dev. Ther.,2018

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1. Silibinin is a suppressor of the metastasis-promoting transcription factor ID3;Phytomedicine;2024-06

2. Is the C-Terminal Domain an Effective and Selective Target for the Design of Hsp90 Inhibitors against Candida Yeast?;Microorganisms;2023-11-22

3. Recent advances toward the development of Hsp90 C-terminal inhibitors;Bioorganic & Medicinal Chemistry Letters;2023-01

4. Silibinin Overcomes EMT-Driven Lung Cancer Resistance to New-Generation ALK Inhibitors;Cancers;2022-12-11

5. Browning of the white adipose tissue regulation: new insights into nutritional and metabolic relevance in health and diseases;Nutrition & Metabolism;2022-09-06

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