Structure-based screening of low-affinity compounds

Author:

Carr Robin,Jhoti Harren

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology

Reference36 articles.

1. Milne, G.M. (2001) Accelerating R&D productivity. Presented at IBC's Drug Discovery Technology World Congress, Boston, MA, USA, 13–15 August 2001

2. Science, art and drug discovery: a personal perspective;Campbell;Clin. Sci.,2000

3. Is there a difference between leads and drugs? A Historical Perspective;Oprea;J. Chem. Inf. Comput. Sci.,2001

4. Molecular complexity and its impact on the probability of finding leads for drug discovery;Hann;J. Chem. Inf. Comput. Sci.,2001

5. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings;Lipinski;Adv. Drug Delivery Rev.,2001

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