Etrolizumab versus adalimumab or placebo as induction therapy for moderately to severely active ulcerative colitis (HIBISCUS): two phase 3 randomised, controlled trials

Author:

Rubin David T,Dotan Iris,DuVall Aaron,Bouhnik Yoram,Radford-Smith Graham,Higgins Peter D R,Mishkin Daniel S,Arrisi Pablo,Scalori Astrid,Oh Young S,Tole Swati,Chai Akiko,Chamberlain-James Kirsten,Lacey Stuart,McBride Jacqueline,Panés Julian,Abdulkhakov Rustem,Abu Bakar Norasiah,Aguilar Humberto,Aizenberg Diego,Akpinar Hale,Akriviadis Evangelos,Alexeeva Olga,Alikhanov Bagdadi,Alvarisqueta Andres,Ananthakrishnan Ashwin,Andrews Jane,Arlukowicz Tomasz,Atkinson Nathan,Atug Ozlen,Bafutto Mauro,Balaz Jozef,Bamias George,Banic Marko,Baranovsky Andrey,Barbalaco Neto Guerino,Basaranoglu Metin,Baum Curtis,Baydanov Stefan,Bennetts William,Besisik Fatih,Bhaskar Sudhir,Bielasik Andrzej,Bilianskyi Leonid,Bilir Bahri,Blaha Pavol,Bohman Verle,Borissova Julia,Borzan Vladimir,Bosques-Padilla Francisco,Bouhnik Yoram,Brooker James,Budko Tetiana,Budzak Igor,Bunganic Ivan,Chapman Jonathon,Che' Aun Azlida,Chernykh Tatiana,Chiorean Michael,Chopey Ivan,Christodoulou Dimitrios,Chu Pui Shan,Chumakova Galina,Cummins Andrew,Cunliffe Robert,Cvetkovic Mirjana,Dagli Ulku,Danilkiewicz Wit Cezary,Datsenko Olena,de Magalhães Francesconi Carlos Fernando,Debinski Henry,Deminova Elena,Derova Jelena,Ding John Nik,Dmitrieva Julia,Dolgikh Oleg,Douda Tomas,Drobinski Piotr,Dryden Gerald,Duarte Gaburri Pedro,DuVall George Aaron,Dvorkin Mikhail,Ennis Craig,Erzin Yusuf,Fadieienko Galyna,Fediv Oleksandr,Fedorishina Olga,Fedurco Miroslav,Fejes Roland,Fernandez Jorge,Fernandez Monica Lorena,Flores Lucky,Freilich Bradley,Friedenberg Keith,Fuster Sergio,Gawdis-Wojnarska Beata,Gil Parada Fabio Leonel,Gimenez Edgardo Daniel,Golovchenko Nataliia,Golovchenko Oleksandr,Gonciarz Maciej,Gordon Glenn,Gregus Milos,Grinevich Vladimir,Guajardo Rodriguez Rogelio,Hall Stephen,Hanson John,Hartleb Marek,Hebuterne Xavier,Hendy Peter,Herring Robert,Higgins Peter,Hilal Raouf,Hilmi Ida Normiha,Hlavaty Tibor,Holman Richard,Holtmann Gerald,Hong John,Horvath Frantisek,Hospodarskyy Ihor,Hrstic Irena,Hulagu Sadettin,Ibarra Verdugo Luis Alberto,Ibegbu Ikechukwu,Inns Stephen,Ivashkin Vladimir,Izanec James,Jain Rajesh,Jamrozik-Kruk Zofia,Kamburov Victor,Karagiannis John,Karakan Tarkan,Karczewski Marek,Kasherininova Irina,Katz Seymour,Kaufman Barry,Kazenaite Edita,Kholina Irina,Khurana Sunil,Kiselevska Anzela,Kleczkowski Dariusz,Klymenko Volodymyr,Knezevic Slavko,Kondusz-Szklarz Malgorzata,Korablina Natalya,Korczowski Bartosz,Kosturkov Lyubomir,Kotzev Iskren,Kouklakis Georgios,Koutroubakis Ioannis,Krause Richard,Kronborg Ian,Krstic Miodrag,Krznaric Zeljko,Krzyzanowski Mikolaj,Kulig Grazyna,Kull Karin,Kupcinskas Limas,Lamet Mark,Latinovic Radakovic Tatjana,Leong Rupert,Leung Wai Keung,Levine Henry,Li Michael Kin Kong,Libanez Bessa Campelo Braga Lúcia,Livzan Maria,Lohdanidi Tetiana,Louzada Pereira Maria Helena,Lowe John,Luetic Kresimir,Lukas Milan,Lymar Yurii,Macrae Finlay,Mäelt Anu,Maev Igor,Mamos Arkadiusz,Mantzaris Gerasimos,Margus Benno,Marinova Ivanka,Markevych Inna,Markov Mario,Markovic Srdjan,Marquez Velasquez Juan Ricardo,Mazzoleni Felipe,Mimidis Konstantinos,Mitchell Brent,Moore Gregory,Morales Garza Luis Alonso,Moscatello Salvatore,Mostovoy Yuriy,Mountifield Reme,Nagorni Aleksandar,Neshta Viacheslav,Obrezan Andrey,Oliinyk Oleksandr,Oliveira Santana Silva Genoile,Orzeszko Maria,Pavlenko Vladimir,Pavlov Dimitar,Penkova Mariana,Peric Sasa,Petkov Plamen,Petrov Asen,Petrov Plamen,Petrova Michaela,Phillips Raymond,Pintor Chacon Sergio,Polianskyi Igor,Prystupa Ludmyla,Pugach Mykhailo,Pukitis Aldis,Pumprla Jiri,Pyrogovskyy Volodymyr,Racz Istvan,Radford-Smith Graham,Raja Ali Raja Affendi,Ramos Castañeda Daniel,Ramos Júnior Odery,Rausher David,Rebrov Andrey,Regula Jaroslaw,Rezk Amir,Reznikova Viktoriia,Rishko Iaroslava,Roblin Xavier,Rodoman Grigory,Rojas Rodriguez Carlos Arturo,Rozciecha Jerzy,Rubin David,Rupinski Maciej,Rzucidlo Jacek,Sablin Oleg,Sahin Halil,Samuel Douglas,Scafuto Scotton Antonio,Schnabel Robert,Schulman Michael,Schultz Michael,Scott John,Sedghi Shahriar,Shaban Ahmad,Shapina Marina,Shaposhnikova Natalia,Shchukina Oksana,Sherman Alex,Shumikhina Irina,Simanenkov Vladimir,Simonov Vladislav,Simulionis Giedrius,Skrypnyk Igor,Sliwowski Zbigniew,Smid Jan,Solaiman Mahmood,Soofi Najm,Soufleris Konstantinos,Spassova Zoia,Stanislavchuk Mykola,Stec-Michalska Krystyna,Stifft Jonathas,Stoinov Simeon,Stoyanova Girgina,Sultan Keith,Surace Lindsey,Takov Dimitar,Tälli Jaak,Tankova Ludmila,Tanno Hugo,Tarabar Dino,Tarakji Elias,Tchernev Konstantin,Thin Lena,Thomas Carlton,Tishaeva Irina,Todorova Tsveta,Tokarenko Oleksandr,Tolmanis Ivars,Tomasevic Ratko,Trofimov Vasiliy,Tulassay Zsolt,Unsal Belkis,Uzunova-Genova Alma,Valentine John,Valuyskikh Ekaterina,Vasconcellos Eduardo,Vasileva Galina,Vasylyuk Sergiy,Vaughn Byron,Velazquez Francisco,Vizir Vadym,Vladimirov Borislav,Volfova Miroslava,Vyhnalek Petr,Wallace Ian,Waluga Marek,Watkins William,Weber John,Wiechowska-Kozlowska Anna,Winstead Nathaniel,Wojtkiewicz Pawel,Wozniak-Stolarska Barbara,Yacyshyn Bruce,Yakovlev Alexey,Younes Ziad,Yukie Sassaki Lígia,Yuksel Ilhami,Zachar Jan,Zaltman Cyrla,Zdravkovic Petrovic Natasa,Zhdan Vyacheslav,Zinchenko Maryna,Zymla Maciej

Funder

F. Hoffmann-La Roche Ltd

Publisher

Elsevier BV

Subject

Gastroenterology,Hepatology

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