Effects exerted by otilonium bromide1Spasmomen is the trade name for otilonium bromide, manufactured by Menarini SpA, Firenze (Italy). It is reported in Index Nominum—drug International Directory, 16th Edition, Swiss Pharmaceutical Society, Med Pharma Scientific Publisher, Stuttgart, p. 899, 1995.1 administration on precipitated opioid withdrawal syndrome in rats2The experimental protocol and procedures have been performed according to the regulations of Italian law: D.L. no. 116, 27/01/1992 and with the approval of the local University Committee on Laboratory Animals.2