The H274Y mutation in the influenza A/H1N1 neuraminidase active site following oseltamivir phosphate treatment leave virus severely compromised both in vitro and in vivo-Reference-Cited by-同舟云学术

The H274Y mutation in the influenza A/H1N1 neuraminidase active site following oseltamivir phosphate treatment leave virus severely compromised both in vitro and in vivo

Published:2002-08 Issue:2 Volume:55 Page:307-317
ISSN:0166-3542
Container-title:Antiviral Research
language:en
Short-container-title:Antiviral Research

Author:

Ives J.A.L.,Carr J.A.,Mendel D.B.,Tai C.Y.,Lambkin R.,Kelly L.,Oxford J.S.,Hayden F.G.,Roberts N.A.

Publisher

Elsevier BV

Subject

Virology,Pharmacology

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4. Influenza virus carrying an R292K mutation in the neuraminidase gene is not transmitted in ferrets;Carr;Antivir. Res.,2001

5. Phenotypic and genoptypic assay of influenza virus neuraminidase indicates a low incidence of viral drug resistance during treatment with oseltamivir;Covington;J. Clin. Virol.,2000

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