Approaching a new era for hepatitis C virus therapy: inhibitors of the NS3-4A serine protease and the NS5B RNA-dependent RNA polymerase

Author:

De Francesco Raffaele,Tomei Licia,Altamura Sergio,Summa Vincenzo,Migliaccio Giovanni

Publisher

Elsevier BV

Subject

Virology,Pharmacology

Reference143 articles.

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3. Altamura, S., Tomei, L., Koch, J.O., Neuner, P.J.S., Summa, V., 2000. Diketoacid-derivatives as inhibitors of viral polymerases. Int. Patent Appl. WO 00/06529. Istituto di Ricerche di Biologia Molecolare P. Angeletti, SpA.

4. The solution structure of the N-terminal proteinase domain of the hepatitis C virus (HCV) NS3 protein provides new insights into its activation and catalytic mechanism;Barbato;J. Mol. Biol.,1999

5. Innovation: hepatitis C virus replicons: potential role for drug development;Bartenschlager;Nat. Rev. Drug Discov.,2002

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