Structural and mechanistic insights into the Keap1-Nrf2 system as a route to drug discovery-Reference-Cited by-同舟云学术

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Structural and mechanistic insights into the Keap1-Nrf2 system as a route to drug discovery

Published:2020-07 Issue:7 Volume:1868 Page:140405
ISSN:1570-9639
Container-title:Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
language:en
Short-container-title:Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Author:

Madden Sarah K.,Itzhaki Laura S.

Funder

CRUK Biotherapeutic Drug Discover

Pancreatic Cancer Research Fund

BBSRC Doctoral Training Scholarship

Society of Chemical Industry

Publisher

Elsevier BV

Subject

Molecular Biology,Biochemistry,Biophysics,Analytical Chemistry

Reference75 articles.

1. Molecular mechanisms activating the Nrf2-Keap1 pathway of antioxidant gene regulation;Kobayashi;Antioxid. Redox Signal.,2005

2. Molecular cross-talk between the NRF2/KEAP1 signaling pathway, autophagy, and apoptosis;Stępkowski;Free Radic. Biol. Med.,2011

3. Molecular mechanisms of the Keap1–Nrf2 pathway in stress response and cancer evolution;Taguchi;Genes Cells,2011

4. Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression;McMahon;J. Biol. Chem.,2003

5. The Keap1-Nrf2-ARE pathway as a potential preventive and therapeutic target: an update;Lu;Med. Res. Rev.,2016

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