Practical syntheses of the C12–C21 epothilone subunit via catalytic asymmetric reductions: Itsuno–Corey oxazaborolidine reduction and asymmetric Noyori hydrogenation
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference23 articles.
1. Epothilone A and B—Novel 16-Membered Macrolides with Cytotoxic Activity: Isolation, Crystal Structure, and Conformation in Solution
2. Activities of the Microtubule-stabilizing Agents Epothilones A and B with Purified Tubulin and in Cells Resistant to Paclitaxel (Taxol®)
3. The Biology and Medicinal Chemistry of Epothilones
4. Chemical Biology of Epothilones
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1. Asymmetric hydrogenation of exocyclic γ,δ-unsaturated β-ketoesters to functionalized chiral allylic alcohols via dynamic kinetic resolution;Chemical Science;2021
2. Itsuno's reagent;Catalysis from A to Z;2020-04-19
3. A Scalable Approach for the Synthesis of Epothilone Thiazole Fragment (C12–C21 unit) Via Wacker Oxidation;Synlett;2018-02-22
4. Coordination determined chemo- and enantioselectivities in asymmetric hydrogenation of multi-functionalized ketones;Coordination Chemistry Reviews;2018-01
5. Preparation of γ,δ-unsaturated-β-ketoesters: Lewis acid-catalysed C H insertion of ethyl diazoacetate into α,β-unsaturated aldehydes;Tetrahedron Letters;2017-09
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