Secondary alcohols act as better nucleophiles than primary alcohols in the lipase-catalyzed regioselective deacylation of dihydroxybenzenes acylated at both phenolic hydroxyls
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference12 articles.
1. Biotransformations in Organic Chemistry;Faber,2004
2. Enzyme Catalysis in Organic Synthesis;Gais,2002
3. Regioselective deacylation of polyacetoxy aryl-methyl ketones by lipases in organic solvents
4. Lipase-catalysed selective deacetylation of peracetylated benzopyranones
5. Biotransformations in the regioselective deacetylation of polyphenolic peracetates in organic solvents
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1. Comprehensive semisyntheses of catathelasmols C, D, and E from D-glutamic acid, utilizing lipase-catalyzed site-selective reactions on intermediates;Bioscience, Biotechnology, and Biochemistry;2020-07-02
2. Syntheses of Indirubins by Aldol Condensation of Isatins with Indoxyl Anion Generated in situ by Lipase-Catalyzed Deacetylation of Indoxyl Acetate;HETEROCYCLES;2020
3. Site-Selective Synthesis of Acacetin and Genkwanin through Lipase-Catalyzed Deacetylation of Apigenin 5,7-Diacetate and Subsequent Methylation;HETEROCYCLES;2019
4. Lipase-Catalyzed Site-Selective Deacetylation of Sterically Hindered Naphthohydroquinone Diacetate and Its Application to the Synthesis of a Heterocyclic Natural Product;HETEROCYCLES;2019
5. Recent examples of the use of biocatalysts with high accessibility and availability in natural product synthesis;Tetrahedron;2018-07
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