One-pot silyl imidate formation-N-alkylation reactions of amides with propargyl propionates

Author:

Chong Tyler G.,Helbling Alex V.,Graff Remi D.,Downey C. Wade

Funder

Camille and Henry Dreyfus Foundation

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference35 articles.

1. Large-Scale Applications of Amide Coupling Reagents for the Synthesis of Pharmaceuticals;Dunetz;Org. Process Res. Dev.,2016

2. Rethinking Amide Bond Synthesis;Pattabiraman;Nature,2011

3. Recent Developments in Amide Synthesis: Direct Amidation of Carboxylic Acids and Transamidation Reactions;Lanigan;Eur. J. Org. Chem.,2013

4. Recent Developments in Amide Synthesis Using Nonactivated Starting Materials;Ojeda-Porras;J. Org. Chem.,2016

5. A facile synthesis of trisubstituted allenamides by DBU-promoted isomerization of propargylamides;Hirokane;Tetrahedron Lett.,2020

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