Nitromethane as a scavenger of acrylonitrile in the deprotection of synthetic oligonucleotides
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference29 articles.
1. Synthesis of deoxyoligonucleotides on a polymer support
2. Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
3. β-Cyanoethyl N,N-dialkylamino/N-morpholinomonochloro phosphoamidites, new phosphitylating agents facilitating ease of deprotection and work-up of synthesized oligonucleotides
4. Polymer support oligonucleotide synthesis XVIII1.2): use ofβ-cyanoethyi-N,N-dialkylamino-/N-morpholino phosphoramidite of deoxynucleosides for the synthesis of DNA fragments simplifying deprotection and isolation of the final product
5. The 4-[N-Methyl-N-(2,2,2-trifluoroacetyl)amino]butyl Group as an Alternative to the 2-Cyanoethyl Group for Phosphate Protection in the Synthesis of Oligodeoxyribonucleotides
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2. Solid-phase synthesis and properties of stereocontrolled boranophosphate/phosphate and phosphorothioate/phosphate chimeric oligouridylates;Royal Society Open Science;2023-04
3. The Chemical Synthesis of DNA and RNA Oligonucleotides for Drug Development and Therapeutic Applications;Encyclopedia of Cell Biology;2023
4. Quantification of synthetic errors during chemical synthesis of DNA and its suppression by non-canonical nucleosides;Scientific Reports;2022-07-15
5. Solid-phase synthesis of oligouridine boranophosphates using the H-boranophosphonate method with 2′-O-(2-cyanoethoxymethyl) protection;Tetrahedron Letters;2021-12
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