Sodium borohydride mediated reduction of N-Boc protected purines and applications in the synthesis of 7-alkyladenines and tetrahydro[1,4]diazepino-[1,2,3-gh]purines
Author:
Funder
Norwegian Research Council
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
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1. Regiospecific Alkylation of 6-Chloropurine and 2,6-Dichloropurine at N7 by Transient Protection of N3/N9 by Methylcobaloxime
2. Chemical reactivity of alkylguanines. I. Methylation of O6-methylguanine derivatives
3. Regioselective Synthesis and Antiviral Activity of Purine Nucleoside Analogues with Acyclic Substituents at N7
4. A Simple Solution to the Age Old Problem of Regioselective Functionalization of Guanine: First Practical Synthesis of Acyclic N9- and/or N7-Guanine Nucleosides Starting from N2,N9-Diacetylguanine
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4. Crystal structures of the synthetic intermediate 3-[(6-chloro-7H-purin-7-yl)methyl]cyclobutan-1-one, and of two oxetanocin derivatives: 3-[(6-chloro-8,9-dihydro-7H-purin-7-yl)methyl]cyclobutan-1-ol and 3-[(6-chloro-9H-purin-9-yl)methyl]cyclobutan-1-ol;Acta Crystallographica Section E Crystallographic Communications;2019-05-03
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