Controlling the radical 5-exo-trig cyclization, and selective synthesis of seco-iso-cyclopropylfurano[e]indoline (seco-iso-CFI) and seco-cyclopropylthiophene[e]indoline (seco-CTI) DNA alkylating subunit of the duocarmycins-Reference-Cited by-同舟云学术

Controlling the radical 5-exo-trig cyclization, and selective synthesis of seco-iso-cyclopropylfurano[e]indoline (seco-iso-CFI) and seco-cyclopropylthiophene[e]indoline (seco-CTI) DNA alkylating subunit of the duocarmycins

Published:2013-08 Issue:35 Volume:54 Page:4756-4759
ISSN:0040-4039
Container-title:Tetrahedron Letters
language:en
Short-container-title:Tetrahedron Letters

Author:

Patil Pravin,Cousins Karalyne,Smith Mallory,Wieskamp Sarah,Ferrara Maddi,Bruce Chrystal D.,Lee Moses

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference27 articles.

1. Shape-Dependent Catalysis: Insights into the Source of Catalysis for the CC-1065 and Duocarmycin DNA Alkylation Reaction

2. CC-1065 and the Duocarmycins: Understanding their Biological Function through Mechanistic Studies

3. CC-1065 and the duocarmycins: unraveling the keys to a new class of naturally derived DNA alkylating agents.

4. The Duocarmycins: Synthetic and Mechanistic Studies

5. Structure and activity relationship of several novel CC-1065 analogs

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Design, synthesis, nuclear localization, and biological activity of a fluorescent duocarmycin analog, HxTfA;Bioorganic & Medicinal Chemistry Letters;2018-05

2. Synthesis and evaluation of duocarmycin SA analogs incorporating the methyl 1,2,8,8a-tetrahydrocyclopropa[c]imidazolo[4,5-e]indol-4-one-6-carboxylate (CImI) alkylation subunit;Bioorganic & Medicinal Chemistry;2016-10

3. A Short Review on the Synthetic Strategies of Duocarmycin Analogs that are Powerful DNA Alkylating Agents;Anti-Cancer Agents in Medicinal Chemistry;2015-05-14

4. Synthetic approaches, functionalization and therapeutic potential of quinazoline and quinazolinone skeletons: The advances continue;European Journal of Medicinal Chemistry;2015-01

5. An efficient synthesis of furano analogs of duocarmycin C1 and C2: seco-iso-cyclopropylfurano[e]indoline-trimethoxyindole and seco-cyclopropylfurano[f]quinoline-trimethoxyindole;Tetrahedron Letters;2014-05