Synthesis of 11-aza-artemisinin derivatives using the Ugi reaction and an evaluation of their antimalarial activity
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference17 articles.
1. Shrinking the malaria map: progress and prospects
2. Combination Therapy for Malaria
3. Synthesis and reactions of 11-azaartemisinin and derivatives
4. Ring opening of artemisinin (qinghaosu) and dihydroartemisinin and interception of the open hydroperoxides with Formation of N-oxides — a chemical model for antimalarial mode of action
5. Syntheses and Antimalarial Activities of N-Substituted 11-Azaartemisinins
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1. New hydrazide derivatives of N‐amino‐11‐azaartemisinin as promising epidermal growth factor receptor inhibitors for therapeutic development in triple‐negative breast cancer;Archiv der Pharmazie;2024-09-13
2. Design, Synthesis, and Antitumor Activity Evaluation of Artemisinin Bivalent Ligands;Molecules;2024-01-15
3. Novel hydrazone derivatives of N-amino-11-azaartemisinin with high order of antimalarial activity against multidrug-resistant Plasmodium yoelii nigeriensis in Swiss mice via intramuscular route;Bioorganic & Medicinal Chemistry Letters;2022-02
4. Six-Membered Rings With 1,2,4-Oxygen or Sulfur Atoms;Comprehensive Heterocyclic Chemistry IV;2022
5. Multicomponent Synthesis: Cohesive Integration of Green Chemistry Principles;Methods in Pharmacology and Toxicology;2021-12-14
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