Selective deprotection of benzyl (Bn) ethers in the presence of para-methoxybenzyl (PMB) ethers-Reference-Cited by-同舟云学术

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Selective deprotection of benzyl (Bn) ethers in the presence of para-methoxybenzyl (PMB) ethers

Published:2015-03 Issue:11 Volume:56 Page:1420-1422
ISSN:0040-4039
Container-title:Tetrahedron Letters
language:en
Short-container-title:Tetrahedron Letters

Author:

Li Xiaohua,Saleh Zachary,Egri Brian,Hourani Ali,Harding Luke,Baryal Kedar N.,Zhu Jianglong

Funder

University of Michigan-Dearborn

University of Toledo

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference10 articles.

1. Greene’s Protective Groups in Organic Synthesis;Wuts,2006

2. Specific removal of o-methoxybenzyl protection by DDQ oxidation.

3. Protection of alcohols as their (p-methoxybenzyloxy)methyl ethers.

4. Selective hydrogenolysis of the benzyl protecting group for hydroxy function with raney nickel in the presence of the MPM (4-methoxybenzyl) and DMPM (3,4-dimethoxybenzyl) protecting groups

5. Reductive cleavage of benzyl ethers with lithium naphthalenide. A convenient method for debenzylation

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