Synthesis and structure determination of SCR7, a DNA ligase inhibitor
Author:
Funder
Goucher College
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference14 articles.
1. Rational Design of Human DNA Ligase Inhibitors that Target Cellular DNA Replication and Repair
2. An Inhibitor of Nonhomologous End-Joining Abrogates Double-Strand Break Repair and Impedes Cancer Progression
3. SCR7 is neither a selective nor a potent inhibitor of human DNA ligase IV
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1. Small-molecule enhancers of CRISPR-induced homology-directed repair in gene therapy: A medicinal chemist’s perspective;Drug Discovery Today;2022-09
2. Bicyclic 6-6 Systems: Pteridines;Comprehensive Heterocyclic Chemistry IV;2022
3. A Universal System of CRISPR/Cas9-Mediated Gene Targeting Using All-in-One Vector in Plants;Frontiers in Genome Editing;2020-11-25
4. One-Pot Synthesis of 7-(Benzimidazol-2-yl)thioxolumazine and -lumazine Derivatives via H2SO4-Catalyzed Rearrangement of Quinoxalinones When Exposed to 5,6-Diamino-2-mercapto- and 2,5,6-Triaminopyrimidin-4-ols;The Journal of Organic Chemistry;2018-11-15
5. Autocyclized and oxidized forms ofSCR7 induce cancer cell death by inhibiting nonhomologousDNAend joining in a LigaseIVdependent manner;The FEBS Journal;2018-10-08
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