Synthetic applications of a three-component Mannich reaction. Total synthesis of IL-6 inhibitor (+)-madindoline A and B
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference20 articles.
1. Madindoline, a Novel Inhibitor of IL-6 Activity from Streptomyces sp. K93-0711. I. Taxonomy, Fermentation, Isolation and Biological Activities.
2. Madindolines, Novel Inhibitors of IL-6 Activity from Streptomyces sp. K93-0711. II. Physico-chemical Properties and Structural Elucidation.
3. Suppression of bone resorption by madindoline A, a novel nonpeptide antagonist to gp130
4. Total Synthesis of (+)-Madindoline A and (−)-Madindoline B, Potent, Selective Inhibitors of Interleukin 6. Determination of the Relative and Absolute Configurations
5. Short Total Synthesis of (+)-Madindolines A and B
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