Conversion of methyl ketones and methyl sulfones into α-deutero-α,α-difluoromethyl ketones and α-deutero-α,α-difluoromethyl sulfones in three synthetic steps-Reference-Cited by-同舟云学术

Conversion of methyl ketones and methyl sulfones into α-deutero-α,α-difluoromethyl ketones and α-deutero-α,α-difluoromethyl sulfones in three synthetic steps

Published:2017-02 Issue:5 Volume:58 Page:396-400
ISSN:0040-4039
Container-title:Tetrahedron Letters
language:en
Short-container-title:Tetrahedron Letters

Author:

Sowaileh Munia F.,Han Changho,Hazlitt Robert A.,Kim Eun Hoo,John Jinu P.,Colby David A.

Funder

University of Mississippi, the American Association of Colleges of Pharmacy as a New Pharmacy Faculty Research Award, the National Institute on Aging

National Institute of General Medical Sciences

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference31 articles.

1. Fluorine in Pharmaceuticals: Looking Beyond Intuition

2. The Many Roles for Fluorine in Medicinal Chemistry

3. Deuterated drugs draw heavier backing

4. Deuterated drugs: where are we now?

5. Tritium release from [19-3H]-19,19-difluoroandrost-4-ene-3,17-dione during inactivation of aromatase

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