Highly diastereoselective chemoenzymatic synthesis of (2′R)- and (2′S)-2′-deoxy[2′-2H]guanosines
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference18 articles.
1. Specifically 2-monodeuterated 2-deoxy-D-riboses (2(S)- and 2(R)-deuterio-2-deoxy-D-erythropentoses)
2. Stereochemistry of deoxygenation of ribonucleotides. Specifically 2'-monodeuterated 2'-deoxycytidines
3. Nucleic acid related compounds. 27. "Virtual coupling" of the anomeric proton of cyclic 2'-deoxynucleoside 3',5'-monophosphates. Reassessment of conformation using praseodymium shifts and assignment of H-2',2 signals by biomimetic deuteration at C-2'
4. Nucleic acid related compounds. 42. A general procedure for the efficient deoxygenation of secondary alcohols. Regiospecific and stereoselective conversion of ribonucleosides to 2'-deoxynucleosides
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3. Synthesis of 9-β-d-arabinofuranosylguanine by combined use of two whole cell biocatalysts;Bioorganic & Medicinal Chemistry Letters;2009-08
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