SNAr reactions of 5-bromo-2-chloro-4-fluoro-3-iodopyridine and its 3-substituted analogs

Author:

Porter Gerard,Saulnier Mark,Wu Yong-Jin

Funder

Bristol-Myers Squibb

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference22 articles.

1. Heterocycles and medicine: a survey of the heterocyclic drugs approved by the U.S. FDA from 2000 to present;Wu;Progress Heterocyclic Chem.,2000

2. Role of Pyridines in Medicinal Chemistry and Design of BACE1 Inhibitors Possessing a Pyridine Scaffold;Hamada,2018

3. Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design;Meanwell;J. Med. Chem.,2011

4. Rings in drugs;Taylor;J. Med. Chem.,2014

5. Metal-free multicomponent syntheses of pyridines;Allais;Chem. Rev.,2014

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