A modified Prins reaction for the facile synthesis of structurally diverse substituted 5-(2-hydroxyethyl)-3,3-dihydrofurane-2(3H)-ones
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
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1. Increased rigidity and bioisosteric replacement in the design, synthesis and preliminary evaluation of novel, functionalized 3,3-dialkyl-γ-butyrolactones as sigma-2 ligands;Medicinal Chemistry Research;2023-12-29
2. Design, synthesis, and evaluation of novel, selective γ-butyrolactones sigma-2 ligands;Medicinal Chemistry Research;2021-07-28
3. Insights into the chemistry and therapeutic potential of furanones: A versatile pharmacophore;European Journal of Medicinal Chemistry;2019-06
4. Synthesis of β,β-Disubstituted γ-Butyrolactones by Chemoselective Oxidation of 1,4-Diols and γ-Hydroxy Olefins with RuCl3/NaIO4;Synlett;2015-01-07
5. Homologation as a lead modification approach en route to a series of lactone-based muscarinic ligands;Medicinal Chemistry Research;2013-08-22
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