Low temperature dehydrogenation of α-indoline nucleosides
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference10 articles.
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2. Direct Evidence for the Conformational Deformation of the Corrin Ring by the Nucleotide Base in Vitamin B12: Synthesis and Solution Spectroscopic and Crystal Structure Analysis of Co.beta.-Cyanoimidazolylcobamide
3. Capture of a Labile Substrate by Expulsion of Water Molecules from the Active Site of Nicotinate Mononucleotide:5,6-Dimethylbenzimidazole Phosphoribosyltransferase (CobT) from Salmonella enterica
4. Brown, K. L.; Chandra, T.; Zou, S.; Valente, E. J. Chem. Commun., communicated. The indoline nucleosides were synthesized by coupling freshly prepared, silylated dimethylindoline/indoline base to an anomeric mixture of the protected sugar 2,3-O-(1-methylethylidene)5-O-(triphenylmethyl)α/β-d-ribofuranose by using 2-fluoro-1-methylpyridinium-p-toluenesulfonate as a condensing agent in 90–96% yield
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