1. Anxiolytic Activity of the MGLU2/3 Receptor Agonist LY354740 on the Elevated Plus Maze is Associated with the Suppression of Stress-Induced c-Fos in the Hippocampus and Increases in c-Fos Induction in Several Other Stress-Sensitive Brain Regions
2. Pedregal, C. Peptide Prodrug Design for Improving Oral Absorption; Abstracts of Papers, 228th American Chemical Society National Meeting, Philadelphia, PA; August 22–26, 2004.
3. Dipeptides as Effective Prodrugs of the Unnatural Amino Acid (+)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY354740), a Selective Group II Metabotropic Glutamate Receptor Agonist
4. Design, Synthesis, and Pharmacological Characterization of (+)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY354740): A Potent, Selective, and Orally Active Group 2 Metabotropic Glutamate Receptor Agonist Possessing Anticonvulsant and Anxiolytic Properties
5. For experimental procedures described in Scheme 1 and the corresponding characterization data, see: Bueno Melendo, A. B.; Coffey, D. S.; Dantzig, A. H.; De Dios, A.; Dominguez-Fernadez, C.; Herin, M.; Hillgren, K. M.; Martin, J. A.; Martin-Cabrejas, L. M.; Martinez-Grau, M. A.; Massey, S. M.; Moher, E. D.; Monn, J. A.; Montero Salgado, C.; Pedersen, S. W.; Pedregal-Tercero, C.; Sweetana, S. A.; Valli, M. J. Preparation of Prodrugs of Excitatory Amino Acids; WO 0255481.