Alternative synthetic route to annulated diaminopyrimidines

Author:

Erdmann Alexandre,Halby Ludovic,Cantagrel Frédéric,Sautel François,Massiot Georges,Arimondo Paola B.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference22 articles.

1. Bergeron, P.; Cohen, F.; Estrada, A.; Koehler, M. F. T.; Lau, K. H. L.; Ly, C.; Lyssikatos, J. P.; Ortwine, D. F.; Pei, Z.; Zhao, X. In Pyrimidine compounds, compositions and methods of use, Patent WO2010014939A1, 2010.

2. 5,6,7,8-Tetrahydropyrido[4,3-d]pyrimidines as novel class of potent and highly selective CaMKII inhibitors

3. Capelli, A.; Marchionni, C.; Micheli, F.; Pasquarello, A.; Perini, B.; St-Denis, Y. In Fused pyrimidines as antagonists of the corticotropinreleasing factor (CRF), Patent WO02088095A1, 2002.

4. Hiranum, H.; Mizogami, S.; Mori, M.; Sekiya, T.; Hanatsuka, M.; Kanayama, T. In 5,6 Alkylenepyrimidine derivatives, processes for preparing the same and pharmaceutical compositions, Patent EP0022481A1, 1981.

5. Pyrimidine derivatives. VII. Structure-activity relationship of hypoglycemic 4-amino-2-(1-piperazinyl)pyrimidines investigated by the adaptive least-squares method.

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