Two-step N-acylindazole to N-alkylindazole reduction. Further synthetic studies on the serotonergic agonist AL-34662-Reference-Cited by-同舟云学术

Two-step N-acylindazole to N-alkylindazole reduction. Further synthetic studies on the serotonergic agonist AL-34662

Published:2008-04 Issue:15 Volume:49 Page:2348-2350
ISSN:0040-4039
Container-title:Tetrahedron Letters
language:en
Short-container-title:Tetrahedron Letters

Author:

Conrow Raymond E.,Delgado Pete,Dean W. Dennis,Callen Gary R.,Plummer Scott V.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference34 articles.

1. 1-((S)-2-Aminopropyl)-1H-indazol-6-ol: A Potent Peripherally Acting 5-HT2 Receptor Agonist with Ocular Hypotensive Activity

2. AL-34662: A Potent, Selective, And Efficacious Ocular Hypotensive Serotonin-2 Receptor Agonist

3. For details see the examples and relevant discussion in: Conrow, R. E.; Delgado, P.; Dean, W. D.; Pierce, D. R.; Gaines, M. S. U.S. Patent 6,998,489B1.

4. Delgado, P.; Conrow, R. E.; Dean, W. D. PCT WO2004/058725A1.

5. Synthetic studies of 14-membered cyclopeptide alkaloids

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