A practical, multigram synthesis of the 2-(2-(4-alkoxyphenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)acetamide (DPA) class of high affinity translocator protein (TSPO) ligands
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
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1. An automated radiosynthesis of [18F]DPA-714 on a commercially available radiosynthesizer, Elixys Flex/Chem;Applied Radiation and Isotopes;2022-02
2. Adventures in Translocation: Studies of the Translocator Protein (TSPO) 18 kDa;Australian Journal of Chemistry;2021
3. Synthesis and evaluation of novel potent TSPO PET ligands with 2-phenylpyrazolo[1,5-a]pyrimidin-3-yl acetamide;Bioorganic & Medicinal Chemistry;2019-09
4. Novel potential pyrazolopyrimidine based translocator protein ligands for the evaluation of neuroinflammation with PET;European Journal of Medicinal Chemistry;2018-11
5. Derivatives of the pyrazolo[1,5- a ]pyrimidine acetamide DPA-713 as translocator protein (TSPO) ligands and pro-apoptotic agents in human glioblastoma;European Journal of Pharmaceutical Sciences;2017-01
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