Decreased TET2/5-hmC reduces the integrity of the epidermal barrier via epigenetic dysregulation of filaggrin in psoriatic lesions
Author:
Funder
National Natural Science Foundation of China
Natural Science Basic Research Program of Shaanxi Province
Publisher
Elsevier BV
Reference39 articles.
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2. TNF-α downregulates filaggrin and loricrin through c-Jun N-terminal kinase: role for TNF-α antagonists to improve skin barrier;Kim;J. Investig. Dermatol.,2011
3. The discovery and function of filaggrin;Hoober;Int. J. Mol. Sci.,2022
4. Revisiting the roles of filaggrin in atopic dermatitis;Moosbrugger-Martinz;Int. J. Mol. Sci.,2022
5. Loss-of-function variants of the filaggrin gene are not major susceptibility factors for psoriasis vulgaris or psoriatic arthritis in German patients;Hüffmeier;J. Investig. Dermatol.,2007
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