Dysregulation of autophagy in melanocytes contributes to hypopigmented macules in tuberous sclerosis complex

Author:

Yang Fei,Yang Lingli,Wataya-Kaneda Mari,Hasegawa Junya,Yoshimori Tamotsu,Tanemura Atsushi,Tsuruta Daisuke,Katayama Ichiro

Funder

Ministry of Education, Culture, Sports, Science and Technology of Japan

Practical research project for rare and intractable diseases

Clinical research project for rare and intractable diseases

Publisher

Elsevier BV

Subject

Dermatology,Molecular Biology,Biochemistry

Reference52 articles.

1. Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34;van Slegtenhorst;Science,1997

2. Identification of tuberin, the tuberous sclerosis-2 product. Tuberin possesses specific Rap1GAP activity;Wienecke;J. Biol. Chem.,1995

3. Activated mammalian target of rapamycin pathway in the pathogenesis of tuberous sclerosis complex renal tumors;Kenerson;Cancer Res.,2002

4. TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth;Inoki;Cell,2006

5. Depigmented nevi the earliest sign of tuberous sclerosis;Gold;Pediatrics,1965

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