Human thrombocytes are able to induce a myocardial dysfunction in the ischemic and reperfused guinea pig heart mediated by free radicals-role of the GPIIb/IIIa-blocker tirofiban

Author:

Seligmann Christian,Simsek Yusuf,Schimmer Mike,Leitsch Tobias,Bock Andreas,Schultheiss Heinz-Peter

Publisher

Elsevier BV

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference20 articles.

1. Platelet activation in unstable coronary disease;Fitzgerald;New England Journal of Medicine,1986

2. Role of platelets and thrombosis in coronary atherosclerotic disease and sudden death;Fuster;Journal of the American College of Cardiology,1985

3. Platelet glycoprotein IIb/IIIa receptors in cardiovascular medicine;Lefkovits;New England Journal of Medicine,1995

4. Regulation of platelet adhesion to the vessel wall;Sixma;Annals of the New York Academy of Sciences,1994

5. GP IIb/IIIa antagonists. Clinical experience and potential uses in cardiology;Kleiman;Drugs in Research and Development,1999

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