Phenobarbital induces monkey brain CYP2E1 protein but not hepatic CYP2E1, in vitro or in vivo chlorzoxazone metabolism

Author:

Lee Anna M.,Joshi Meenal,Yue Jiang,Tyndale Rachel F.

Publisher

Elsevier BV

Subject

Pharmacology

Reference36 articles.

1. Role of polymorphic CYP2E1 and CYP2D6 genes in NNK-induced chromosome aberrations in cultured human lymphocytes;Abdel-Rahman;Pharmacogenetics,2000

2. Chlorzoxazone 6-hydroxylase and p-nitrophenol hydroxylase as the most suitable activities for assaying cytochrome P450 2E1 in cynomolgus monkey liver;Amato;Drug Metab. Dispos.,1998

3. Differential induction of human liver UDP-glucuronosyltransferase activities by phenobarbital-type inducers;Bock;Biochem. Pharmacol.,1987

4. Oxidative stress, toxicology, and pharmacology of CYP2E1;Caro;Annu. Rev. Pharmacol. Toxicol.,2004

5. Quantification of the expression and inducibility of 12 rat cytochrome P450 isoforms by quantitative RT-PCR;Caron;J. Biochem. Mol. Toxicol.,2005

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